Page 9 - Spring2009
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Letters








                  so many molecules of human manufac-  the Teflon-like polymers. Here fluorine  thing, or at least the swath of problems
                  ture (industry and pharmaceuticals).  atom(s)  are  used  to  manipulate  the  in the article, on this one type of atom.
                     First is the elemental form, a di-  properties of the molecules involved.        Mark Lichtenstein, BA,
                  atomic molecule of tremendous reactiv-  For instance, ordinary ethyl ether has             MS Chemistry
                  ity, exceeding that of other oxidizers.  a long history as an anesthetic, but it is   Waymart, Pennsylvania
                  As the reviewer notes, it is not found  very explosive. Fluorinated ethers retain
                  in nature due to its tremendous reactiv-  their anesthetic properties but are far  Reply from Andreas Schuld, of Parents
                  ity.                               less flammable.                     of Fluoride Poisoned Children (PFPC):
                     Second, the element fluorine ap-    According to the article, the ad-  The claim that fluoride can harden den-
                  pears as fluorine ions either in solution  verse effects of certain drugs are linked  tal structure to avoid tooth decay has
                  or in salts/ionic compounds. The ionic  to their fluorine content. This link is  long been disproven, even by the CDC.
                  form of fluoride is what is used in drink-  tenuous at best. The drugs aren’t like  Fluoride binds preferentially with alu-
                  ing water. The ionic form of fluorine  capsules packaged with “poisonous”  minum, not calcium. In the presence of
                  forms very tight bonds with many posi-  fluorine waiting to be released in the  mere trace amounts of aluminum, toxic
                  tive ions, particularly calcium. This is  body. The fluorine atoms are tightly  fluoroaluminate is formed. Fluoride poi-
                  part of its claim to fame for hardening  attached to the parent molecule and are  soning and its degrees depend on total
                  dental structure to avoid tooth decay.  extremely unlikely to be let loose under  intake, not just the fluoride amounts in
                  However, in large doses it can tie up  conditions that will support life.   water, although the presence of fluoride
                  significant amounts of calcium ions    Further, it is common in drug re-  in water alone can be detrimental and
                  needed for muscular function causing  search to make literally thousands of  fatal, as proven by many studies from
                  muscle failure, such as breathing stops  new molecules to find one that can be  China and India, areas endemic with
                  and heart failure.                 sold. Usually, as the field is narrowed  fluoride poisoning.
                     This acute form of fluoride poison-  down to the molecule that ends up at   Regarding the use of fluoride in
                  ing is not possible from the quantities in  the local pharmacy, a number of related  medications, the scientific literature
                  drinking water; rather, such poisoning  candidates are carried forward in case  shows that many such compounds cause
                  is more likely with a laundry chemical  the “best” molecule has some fault un-  serious fluoride poisoning. The problem
                  containing hydrogen fluoride, which is  covered. Some of those molecules will  of fluoride in medications is very serious
                  sold for removing rust and blood stains.  sometimes have other substances in the  and proper understanding is crucial in
                  If you use that stuff—I don’t let it in the  place of the fluorine atom and still have  providing advice. More than sixty years
                  house—please, please follow the safety  many similar properties to the fluorine-  ago, German scientists showed that all
                  instructions and rinse it out very thor-  containing molecules. The point is that  fluoride compounds— inorganic and
                  oughly. The residues can cause nasty  the presence of fluorine does not make  organic—were able to inhibit thyroid
                  chemical burns that are very slow to  the molecule toxic. Blaming fluoride  hormone metabolism.  This  research
                  heal. Similarly, it was at one time com-  for side effects is sort of like blaming  led  to  the  widespread  use  of  such
                  mon to etch glass with “weak” solutions  accidents on spare tires because almost  compounds as Capacin (3-fluoro-4-
                  of hydrofluoric acid to make pretty de-  all cars involved in accidents have spare  oxy-phenylacetic acid) in the treatment
                  signs. Be aware that these solutions are  tires.                       of hyperthyroidism. In the 1940s, Pro-
                  quite dangerous.                       Putting fluoride in drinking water is  fessor Euler and colleagues from the
                     Third, fluorine can be found cova-  indisputably problematic, granted, as a  University of Breslau were able to cause
                  lently bound to a molecule, such as is in  civil liberties problem, probably also as  identical bone and enamel defects with
                  some pesticides and pharmaceuticals, as  a health issue, but it is far too simplistic  organic fluoride compounds as are es-
                  well as in some polymers, particularly  to lay the blame for just about every-  tablished to occur with inorganic ones,

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