Page 29 - Spring2008
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questionable. For most people living outside 35  list—especially goose liver and goose meat, cheeses and egg yolks—but
                 degrees latitude from the equator, animal foods  natto, a strong-tasting fermented soy food common in Eastern Japan, actu-

                 supply needed vitamin D in the diet.       ally has the highest amount. Natto contains a specific form of vitamin K
                                                                                                                        2
                                                            called menaquinone (MK-7), rather than MK-4, the form found in animal
                 VITAMIN K  2                               products; the relative efficacy of these two forms is currently unknown.

                      Vitamin K is the king of the fat-soluble  It is therefore possible for a vegetarian diet to be rich in vitamin K . Most
                                                                                                                   2
                 vitamins. Vitamins A and D cooperate to tell cells  vegetarians do not consume natto, however, and most vitamin K  con-
                                                                                                                    2
                 which proteins to make; vitamin K is responsible  sumed by participants in the Rotterdam Study came from meat, eggs and
                 for activating these proteins and making them  cheese.
                 functional by conferring upon them the ability
                 to bind calcium. In addition to its classically  VITAMIN B 12
                 understood role in blood clotting, vitamin K is   Vitamin B  is required for the synthesis of new DNA, the degrada-
                                                                         12
                 necessary for the deposition and organization of  tion of certain amino acids, the production of energy, the formation of red
                 calcium salts in bones and teeth; the protection of  blood cells and the formation of myelin, the sheath that insulates neurons.
                 blood vessels, kidneys and other soft tissues from  Its defi ciency occurs in four stages, beginning with declining blood levels
                 abnormal calcification; and the synthesis of im-  of the vitamin (stage I), progressing to low cellular concentrations of the

                                                      20
                 portant lipids involved in brain metabolism.    vitamin (stage II), an increased blood level of homocysteine and a decreased
                      Vitamin K comes in two forms: K  and K .  rate of DNA synthesis (stage III), and fi nally, pernicious anemia (stage IV).
                                                  1     2
                 Vitamin K  is found in green plants, while vitamin  Irreversible nervous system degeneration also occurs in cases of severe
                          1
                 K  is found in animal fats and fermented foods.  defi ciency.
                                                                     24
                   2
                 Vitamin K  is preferentially used for the activa-     Pernicious anemia is a condition in which red blood cells are im-
                          1
                 tion of blood clotting factors, while vitamin K  mature, oversized and cannot function properly. Because DNA synthesis
                                                         2
                 is preferentially used for all of vitamin K’s other  is compromised, the cells do not divide as they should. The disease was
                 functions. The two K vitamins are therefore not  fi rst identifi ed in 1824 and was considered incurably fatal until the 1930s
                 interchangeable. The clearest demonstration of  when physicians discovered that it could be treated with liver. Soon after,
                 this is the fact that only vitamin K  is associated  they found that stomach juice could be used in conjunction with the liver
                                              2
                 with a reduced risk of heart disease. In the Rot-  to enhance its effect.
                                                                             25
                 terdam Study, subjects consumed nearly ten times     Conventional nutritional wisdom considers vitamin B  as the one
                                                                                                              12
                 more K  than K ; a high intake of K  reduced the  vitamin found exclusively in animal products. There are some bacteria
                       1
                                               2
                              2

                 risk of severe arterial calcification by 52 percent  in the small intestine that synthesize absorbable B , but their presence is
                                                                                                      12
                 and reduced heart disease mortality by 57 percent,  unreliable and they face competition from bacteria that synthesize inac-
                 while a high intake of K  had no effect.    tive analogues that compete with B  for absorption.  Most supplements
                                                  21
                                                                                                        26
                                      1                                                   12
                      Figure 3 shows vitamin K  contents of  supply cyanocobalamin, in which each molecule of B  is attached to a
                                                                                                          12
                                              2
                 selected foods. Animal products dominate the  molecule of cyanide. Since vitamin B  detoxifi es cyanide by binding it
                                                                                            12
                                             FIGURE 3. VITAMIN K  CONTENT OF SELECTED FOODS
                                                                2
                   Values taken from references 22 and 23. MK-4 is the type of vitamin K  synthesized by animal bodies from vitamin K .
                                                                                                                       1
                                                                                2
                   Whether it has special value apart from other forms of vitamin K  has yet to be determined.
                                                                         2
                   FOOD              Vitamin K  (mcg/100g)      FOOD                  Vitamin K  (mcg/100g)
                                                                                              2
                                             2
                      Natto              1103.4   (0% MK-4)        Chicken Liver             14.1    (100% MK-4)
                      Goose Liver Paste     369.0  (100% MK-4)     Salami                      9.0     (100% MK-4)
                      Hard Cheeses           76.3  (6% MK-4)       Chicken Breast              8.9    (100% MK-4)
                      Soft Cheeses           56.5  (6.5% MK-4)     Chicken Leg                 8.5    (100% MK-4)
                      Egg Yolk (Netherlands)     32.1   (98% MK-4)  Ground Beef (Medium Fat)     8.1    (100% MK-4)
                      Goose Leg              31.0   (100% MK-4)    Bacon                       5.6    (100% MK-4)
                      Curd Cheeses           24.8  (1.6% MK-4)     Calf Liver                  5.0    (100% MK-4)
                      Egg Yolk (US)          15.5  (100% MK-4)     Sauerkraut                  4.8    (8% MK-4)
                      Butter                 15.0   (100% MK-4)    Salmon                      0.5    (100% MK-4)
                                                                   Mackerel                    0.4    (100% MK-4)
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