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Rush          Early in his career he was appointed Profes-     Rush  developed  the  “heroic  dose”  of

           continued to       sor of Chemistry at the College of Philadelphia.  calomel during the yellow fever epidemic in
                              Rush’s lectures were open to the public and he  Philadelphia in the autumn of 1793. In Septem-
         be vocal in his      espoused chemistry only in its relation to medi-  ber 1793, he came across a book written in 1741,
             support for      cine. He was an excellent orator and was highly  which Benjamin Franklin had given to him many
           heroic doses       esteemed as a chemist, despite his ignorance of  years earlier. As treatment for “bilious fever,” in
                              modern theories of his time (including the exis-
                                                                         particular yellow fever, the book recommended
              of calomel      tence of oxygen, discovered in 1771). He was  “vigorous purges to rid the viscera of their ‘fecu-
            for “virtually    also well published, thanks to supporters such as  lent corruptible contents.’”
                                                                                               30
                    every     Benjamin Franklin, who “encouraged” contribu-     Armed with this information, he developed
                              tions from physicians. In 1774 Rush was chosen  a powder consisting of calomel and jalap, another
                disease,”     as a delegate to the rst Continental Congress and  strong purgative, and recommended that it be

           and calomel        became acquainted with many important histori-  given three times daily. Rush later wrote that the

            became the        cal gures, including George Washington and the  medication “perfectly cured four out of the  rst
                              Adamses, and was a signer of the Declaration of   ve patients to whom I gave it, notwithstanding
            first remedy      Independence. In 1777, after working as a doc-  some of them were advanced several days in the
           of choice for      tor during the Revolutionary War, Rush left his  disorder.” 31

           practitioners      position in Congress and was appointed Surgeon   Rush lost hundreds of patients during the
                              General (later titled “Physician General”) of the  epidemic and prepared so many doses of his “bil-
                  of what     Middle Department of the Continental Army.  ious pills” (made from calomel and jalap) that his
                 became       He resigned this post in 1778 and returned to  hands were rumored to have turned black from
               known as       Philadelphia, at which point he became one of  the mercury. Even though a great many patients
                              the most inuential gures, for better or worse, in  died “despite” the heavy doses of calomel and


                  “heroic     American medical history. Much of his inuence  bleeding and despite the attacks on Rush by his

              medicine.”      came as a teacher; between 1779 and 1812 he  fellow doctors, who did not agree with the harsh-
                              taught over 2800 students and apprenticed many  ness of his “heroic” methods, Dr. Rush’s impact
                              more. He also served as chairman of the Theory  on American medicine regarding high doses of
                              and Practice of Physic at what would become the  calomel would continue for another 70 years,
                              University of Pennsylvania, and at one time he  until the end of the Civil War. 32
                              was called “the greatest physician in the United
                              States.” 28                                HEROIC MEDICINE AS STANDARD
                                   His was a time of various “bilious fevers”  ORTHODOX THERAPY
                              and acute diseases, such as typhus, typhoid     Throughout  the  19th  century  medical
                              fever, malaria, cholera, dysentery, yellow fever  knowledge grew tremendously, but during Rush’s
                              and dengue. Practitioners had little knowledge  day, physicians knew little about pathology,
                              of hygiene (although Rush was one of the lead-  diagnostics or physiology. There were as many
                              ers in this area), and most fevers were lumped  schools of thought on these matters as there were
                              together into one illness, with similar treat-  remedies and therapies.
                              ment—bleeding and purging—prescribed for        Men like Rush practiced “heroic medi-
                              all. Rush believed in abstaining from alcohol,  cine,” believing greatly in the bene ts of copious
                              but nevertheless often prescribed it in copious  bleeding and excessive purging; surgeons were
                              amounts as a medicine, for example, with a daily  becoming skilled in operating even though they
                              dose of cinchona bark (from which quinine is  had no anesthesia; there were homeopaths, who
                              derived). According to Binger, “his fondness  believed in minute doses based on the laws of
                              for emetics and purges was much in evidence;  Samuel Hahnemann; the Thomsonians, eclectics
                              ipecacuanha, tartar emetic, calomel and jalap”  and botanists, followed the teachings of Samuel
                              were prescribed “freely;”in fact he believed so  Thomson; the Indian doctors used Native Ameri-
                              strongly in the effects of these medicines that he  can remedies including sweating; and many who
                              helped to organize a free pharmacy for the poor  used combinations of these approaches.
                              in Philadelphia in 1786. 29                     There was no health insurance, no licens-
         24                                         Wise Traditions                               SUMMER 2008
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