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The fact that         If the baby is dehydrated, Campbell-Mc-  SOLUTIONS THAT ARE NO SOLUTION
            Miralax has       Bride recommends adding more water to the    When hydration and dietary changes do not
                              baby’s milk formula. In situations where the  do the trick, or fecal impaction has become a
            never been  baby is producing only small amounts of very  concern, it may become necessary to perform
           approved by        dark urine, the formula initially can be diluted  enemas (for children who will tolerate them)
            the FDA for       almost by half; after the urine normalizes, the  or more occasionally, to resort to glycerin sup-
                              parents can then experiment with different  positories. Disturbingly, one of mainstream
                pediatric  amounts of water to find the correct ratio for  medicine’s top recommendations  for disim-
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            use has not       their baby. (She notes that every child has differ-  paction—and often, its enthusiastic recom-
                 stopped      ent requirements for water, depending on factors  mendation for ongoing “maintenance”—is to
                              such as metabolism, activity level and weather.)
                                                                       administer an “osmotic laxative” featuring a
             health care         Sometimes, dehydration is not the trigger-  highly problematic active ingredient called
               providers      ing factor for infant constipation. Some babies  polyethylene glycol (PEG) 3350. One of the
                              on the raw milk formula find high levels of  leading PEG-3350-containing products is the
                     from  dairy protein constipating. (Formula based on  Bayer-owned, over-the-counter drug Miralax;
           promoting it       raw goat milk is more likely to be constipat-  the fact that Miralax has never been approved by
         as the “go-to”       ing that formula based on raw cow’s milk.) In  the FDA for pediatric use has not stopped health
                              these cases, Campbell-McBride recommends  care providers from promoting it as the “go-to”
             remedy for  switching the infant to the liver-based formula  remedy for constipated children. In fact, across
            constipated       and when the baby is old enough (no earlier  all age groups, Miralax is the second leading
                children.     than four months of age), carefully starting to  “digestive remedy” in the U.S. 23
                                                                           Horror stories abound about PEG 3350’s
                              introduce appropriate solid foods (see “Avoid
                              the Rice Cereal”).                       propensity to cause extreme neuropsychiatric
                                 Large amounts of high-protein dairy—such  side effects, including rage, anxiety and para-
                              as whey, yogurt, kefir and cheese—can also  noia. Between 2007 and 2017, the FDA received
                              aggravate constipation in some older children  reports of over fifteen hundred different adverse
                              and adults.  Deemphasizing these high-protein  reactions to PEG 3350 in children, of which
                                       21
                              dairy foods and replacing them with more high-  nearly three in five were neurological.  A parent
                                                                                                      24
                              fat dairy—butter, ghee and homemade sour  group called Parents Against Miralax has tens
                              cream—can help resolve the issue by lubricating  of thousands of members, many of whom have
                              the gut wall and softening the stool. Campbell-  joined class-action lawsuits.
                              McBride also recommends increasing animal    There is growing evidence that PEG-3350-
                              fat consumption overall as well as prioritizing  based drugs may alter the microbiome and
                              gelatinous meats over muscle meats.      even increase the risk of antibiotic resistance.



                              C-SECTIONS AND INFANT CONSTIPATION: AN UNEXPLORED TOPIC
              A growing body of research indicates that babies delivered by C-section are more likely than vaginally-delivered
          babies to experience chronic health problems later in life, including type 1 diabetes, obesity and asthma.  The hy-
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          pothesis underlying these observations is that infants born by C-section miss out on exposure to the mother’s vaginal
          and intestinal microbiota, and that during vaginal births this exposure plays an important role in “priming” the infant’s
                        32
          immune system.  As one researcher describes it, “Every generation of mothers hands over its microbiome to the next,
          as the baby is coated with beneficial germs while being squeezed through the birth canal—but this doesn’t happen for
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          babies born through C-section.”
              In 2018, Japanese researchers conducted a first-of-its-kind study assessing the potential correlation between C-section
          delivery and infant constipation, expecting that infants not delivered vaginally would have higher rates of constipation
          (as defined by weekly frequency of bowel movements).  Although the study’s results did not bear out the researchers’
                                                        32
          assumptions—instead showing comparable rates of constipation for both modes of delivery—the investigators noted
          that the low overall rate of constipation in Japanese babies (1.37 percent) may have made it difficult to detect meaningful
          differences. Suggestively, they found that C-section babies were significantly less likely to be exclusively breastfed. One
          wonders what such a study might find in the U.S., where constipation and C-sections both occur at alarmingly high levels.

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