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Cannell concluded that neither children nor  memorial by the fishing populations of Scotland,   Physicians
                  adults should use cod liver oil or multivitamins  Sweden, and norway for its general medicinal
                  containing true (pre-formed) vitamin A. Sixteen  and strengthening properties.  for centuries be-  used cod liver
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                  scientists signed on to the paper as co-authors,  fore producing the oil itself, the British used the   oil to treat
                  although this does not mean that each one en-  blackish residue left behind by barreled cod livers   the vitamin
                  dorsed every statement in the paper. Cannell  as a balm.  In 1766, a Manchester Infirmary began
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                  quoted this paper extensively and expanded his  prescribing ingestion of the oil for rheumatism   D deficiency
                  arguments against vitamin A in his December  after a patient cured herself of the disease on two   disease
                  newsletter,  while Dr. Joseph Mercola repeated  occasions by ingesting her topical treatment.  The   rickets at least
                           2
                                                                                                5
                  Cannell’s claims on his web site in two articles  infirmary thereafter used fifty to sixty gallons of
                  published this winter. 3,4                cod liver oil per year, and after comparing its   as far back as
                                                                               6
                      What the scientific literature shows, how-  use to that of a placebo in a number of individual   1799, and by
                  ever, is that vitamins A and D work as partners  patients, the physician Percival added it to the   the 1820s use
                  rather than antagonists. While there is no solid  British Pharmacopoeia in 1771. 5
                  evidence linking vitamin A to increases in mor-     Physicians used cod liver oil to treat the vi-  of cod liver
                  tality or higher rates of infection, vitamin A does  tamin D deficiency disease rickets at least as far   oil for this
                  cause adverse effects such as bone loss when it is  back as 1799, and by the 1820s use of cod liver   purpose was
                  not provided with its molecular partner, vitamin  oil for this purpose was widespread in germany,
                  D. Since cod liver oil provides both partners  holland and the netherlands. During the same   widespread
                  together, it developed a long and successful his-  century, its use expanded to include the treatment   in Germany,
                  tory as an important therapeutic and prophylactic  of eye diseases and tuberculosis.  research be-  Holland
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                  supplement. Many modern cod liver oils are de-  tween 1920 and 1940 further expanded the use of
                  ficient in vitamin D and should be avoided, but  cod liver oil to prevent or treat measles, industrial   and the
                  those providing adequate vitamin D continue to  absenteeism, and puerperal fever, a fatal infection   Netherlands.
                  provide an important natural food source of the  occurring in women just after giving birth. The
                  fat-soluble vitamins.                     advent of sulfa antibiotics and later penicillin
                                                            mostly eliminated the interest in cod liver oil as
                  The OriginS Of COD Liver OiL              an anti-infective agent, but a number of trials
                      Hippocrates first recorded the medicinal use  conducted before 1940 provided solid evidence
                  of fish oils, and the first century naturalist Pliny  of its efficacy. Cod liver oil reduced measles
                  the elder recorded the use of dolphin liver oil as  mortality by more than one-half and reduced
                  a remedy for chronic skin eruptions.  in 1848, the  industrial absenteeism by up to two-thirds in
                                               5
                  British physician John hughes Bennett observed  clinical trials. As a prophylactic, it reduced the
                  that cod liver oil had been used from time im-  incidence of puerperal fever by two-thirds, and as


                                                             ARTICLE SUMMARY

                   •  Mankind has consumed marine liver oils for thousands of years and cod liver oil for at least hundreds of years.
                   •  Several trials conducted before 1940 found that the vitamin A in cod liver oil had powerful anti-infective power, which
                       popularized the oil as a prophylactic and led to its use as a treatment against puerperal fever, measles, and industrial
                       absenteeism.
                   •  Vitamins A and D cooperate with one another. They are not antagonists, but large doses of one may cause harm when
                       not accompanied by the other.
                   •  There is no evidence that vitamin A increases mortality.
                   •  Over a quarter of Americans consume less than half the RDA of vitamin A, which is 3,000 IU per day for adult males.
                       Price’s tooth decay reversal program would have provided over 10,000 IU per day. Sub-optimal intakes of vitamin
                       A may be related to asthma, kidney stones, fatty liver disease, oxidative stress, and susceptibility to environmental
                       toxins.
                   •  During the winter or year-round for people with dark skin, some extra vitamin D from fatty fish or supplements may
                       be necessary for some people.
                   •   High-vitamin cod liver oil is a very useful source of vitamins A and D and omega-3 fatty acids.

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