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mercury thus becomes trapped inside the cells  mercury.  Additionally, testosterone appears to aggravate mercury toxic-
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         and causes ongoing damage.  Mercury has a  ity during development, while estrogen protects against it.  This may
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                                  7
         particular affinity for the brain, where it may  explain why more boys than girls are diagnosed with autism spectrum
         be retained indefinitely.  It also accumulates  disorders and attention deficit disorders.
                             7,8
         in epithelial tissues, organs and glands, such as
         the salivary glands, thyroid, liver, pancreas, tes-  DENTAL AMALGAM FILLINGS
         ticles, prostate, sweat glands and kidneys, and   Dental amalgam, the material used in “silver” fillings beginning in
         the epithelium of the intestinal tract and skin. 7  the nineteenth century, is about 50 percent mercury. Health and dental
             According to the Environmental Protec-  authorities deemed amalgam safe based on studies that were designed to
         tion Agency (EPA), 2-7 percent of women of  detect obvious harm but did not investigate subtle or long-term effects.
         childbearing age in the U.S. have blood mercury  Consequently, a loose scientific consensus has long discounted the idea
         levels of concern.  There is reason to believe that  of mercury toxicity from dental amalgams, pointing to population studies
                       9
         regulatory levels of concern are too lax. A 2012  showing that people with high exposures and even people with a high
         study showed blunted cortisol response and  body burden do not necessarily have toxicity symptoms. Those who blame
         higher inflammatory markers at blood mercury  amalgams for their illnesses have been viewed askance.
         levels well below the EPA’s established level   Mercury is highly volatile, however, and amalgams continuously
         for potential health risks (5.8 micrograms per  off-gas in the mouth. Evidence indicates that exposure from amalgams is
         liter).  In addition, four neurodevelopmental  sufficient to cause harm to susceptible people.  The authors of the mer-
             10
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         disorders (attention-deficit/hyperactivity disor-  cury chapter in the most recent metals toxicology textbook estimate that
         der, autism, seizures and stutter) affect almost  roughly 1 percent of the population is incurring clinical illness from their
         11 percent of all U.S. births, up 30 percent over  dental amalgams.  This calculation is likely to be a gross underestimate
                                                                 7
         the past decade.  Subclinical decrements in  because it excludes other diagnoses that may have a mercury component,
                       11
         brain function are even more common, affecting  such as multiple sclerosis. The World Health Organization (WHO) esti-
         up to 15 percent of births.               mates that the typical absorbed dose of mercury from amalgams is one to
                               12
             Mercury’s toxicity may be amplified by  twenty-two micrograms per day, with most values in the range of one to
         exposure to other toxic metals, including lead,  five micrograms per day.  Various factors, including gum chewing and
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         cadmium and aluminum. Mercury and lead,  bruxism, can increase these exposures to an upper range of about one
         in particular, are highly synergistic. In fact, in  hundred micrograms per day.  Preliminary evidence also suggests that
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         one study, a dose of mercury sufficient to kill 1  certain types of electromagnetic radiation, including EMR from mobile
         percent of lab rats (lethal dose “LD01”), when  phones and from magnetic resonance imaging (MRI) may increase the
         combined with a dose of lead sufficient to kill  release of mercury vapor from dental amalgams. 17
         1 percent, killed 100 percent of the rats.  A   Within the past ten years, human studies have documented over a
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         similar test involving mercury and aluminum  dozen common genetic variants that convey increased susceptibility to
         in cultured neurons killed 60 percent of the cells  mercury,  indicating the fact that genes drive susceptibility (and resis-
                                                          1,18
         when the two low-dose toxicants (LD01) were  tance) to mercury toxicity.  Hundreds more are likely to exist, because
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         combined.  Even antibiotics have been shown  mercury attacks sulfur in proteins and the body has tens of thousands
                  14
         to enhance the uptake, retention and toxicity of  of genetically determined sulfur-containing proteins, many of which


                                  TABLE 1: COMMON SOURCES OF EXPOSURE TO MERCURY


           Types of Exposures        Form of Mercury           Exposure Levels
           Dental amalgams           Mercury vapor             A filling may release a few micro-
                                                               grams of mercury vapor per day
           Dietary fish              Methylmercury             Depending on the species, a portion may contain
                                                               roughly 1 to 100 micrograms of methylmercury
           Vaccines                  Ethylmercury              A thimerosal-containing vaccine may contain 12.5
                                                               to 25 micrograms of ethylmercury per shot
           Prenatal exposures        All forms                 Levels are unknown but clinically significant


         16                                         Wise Traditions                               SPRING 2018
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