Page 31 - Winter2017
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There is no doubt that for some premeno-  human hormones. Contrary to popular belief, a   Contrary
            pausal and menopausal women, bioidentical  hormone formula packaged at a compounding   to popular
            hormone therapy offers much needed relief and  pharmacy is in reality no different than those
            is better than the complications that often arise  formulas obtained from a mainstream phar- belief, a
            without them. The purpose of this article is to  macy. Compounding pharmacies are working   hormone
            assist readers in making informed decisions  with the same synthetic raw material as the com-  formula
            regarding the use of bioidentical hormones and  mercial pharmaceutical companies in creating
            to support those who desire to safely wean off  creams, pills, sprays and patches.   packaged
            bioidenticals while supporting their hypothal-                                     at a
            amus-pituitary-adrenal-gonadal axis (HPAG  ANATOMY OF HUMAN HORMONES               compounding
            axis). It is always advisable that women wean     For many years, the scientific medical
            gradually off bioidentical or synthetic hormones  community believed that hormone replacement  pharmacy

            under the supervision of a licensed physician  therapy (HRT) at any age would reduce the risk   is in reality
            or naturopathic doctor. In my experience, the  of heart attack and stroke. This hope was dashed   no different
            weaning process can be smooth once the Wise  by the Women's Health Initiative study, which
            Traditions diet is implemented daily, meal and  found that taking estrogen plus progestin for  than those
            sleep routines are consistent and certain nutri-  more than five years places postmenopausal   formulas
            tional and homeopathic supports are in place.   women at greater risk for heart attacks, strokes   obtained
                As we consider hormones, keep in mind  and several other serious problems. The study’s
            that each hormone, just like each cell, needs to  conclusion reads, “Overall health risks exceeded  from a
            act in synchrony with every other hormone. No  benefits from use of combined estrogen plus   mainstream
            hormone works in isolation nor are individual  progestin for an average 5.2-year follow-up   pharmacy.
            hormones immune to the influence of other  among healthy postmenopausal U.S. women.
            hormones.                                 All-cause mortality was not affected during
                                                      the trial. The risk-benefit profile found in this
            ANATOMY OF                                trial is not consistent with the requirements for
            BIOIDENTICAL HORMONES                     a viable intervention for primary prevention of
                Bioidentical hormones are hormones de-  chronic diseases, and the results indicate that
            rived from plants, such as soy or wild yams, and  this regimen should not be initiated or continued
            are designed to be structurally identical to the  for primary prevention of CHD [coronary heart
            hormones produced naturally inside the human  disease].” 3
            body. The claim is that “they are the closest     All human sex hormones are derived from
            and most natural form of exogenous hormones  cholesterol. The body manufactures roughly 80
            possible and yet they are identical to our own  percent of the cholesterol needed to maintain a
            endogenous hormones.”                     healthy endocrine system. The remaining 20
                According to Dr. Laura Streicher, MD,  percent comes from exogenous dietary sources,
            “The only thing that is natural is to drink the  primarily animal fat in the form of egg yolks,
            horse urine or eat the soy plant (both are used  butter fat, lard and bacon, tallow and beef fat,
            in the manufacturing of hormones). All plant-  duck and goose fat, schmaltz and poultry skin,
            derived hormone preparations, whether they  fish skin, fish eggs and wild seafood. Choles-
            come from a compounding pharmacy or a large  terol is the precursor to pregnenolone. From
            commercial pharmacy, require a chemical pro-  pregnenolone, our sex and adrenal organs
            cess to synthesize the final product, which can  produce estrogens, progestins (progesterone)
            then be put into a cream, a spray, a patch or a  and testosterone (as well as DHEA, DHT and
            pill. Promoters of compounded plant-derived  androstenedione).
            hormones use the terms 'natural' and 'bioiden-     Hormones are made in the pineal gland,
            tical' because it is appealing to consumers and  hypothalamus, pituitary, parathyroid, thyroid,
            implies that it is not synthetic.” 2      adrenals, thymus, pancreas, ovaries, testes and
                Plant-derived estrogen from soybeans is  adipose tissue. Each of these glands play a role
            molecularly very similar but not identical to  in the symphony of hormone production. It is

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